Description
Product Characteristics: FUNCTION: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K+. May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca2+ or Mg2+. Subcellular location: Membrane, Multi-pass membrane protein Tissue specificity: Testis-specific. Mainly expressed in spermatocytes.,Calcium-activated,Potassium channel subfamily U member 1, Calcium activated potassium channel subunit alpha 3, Calcium-activated potassium channel, subfamily M subunit alpha-3, Slowpoke homolog 3, Slo3, pH sensitive maxi potassium channel, KCNMA3, KCNMC1, SLO3
Target Information: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+) (By similarity)